PICO scheme: The method for systematic and structured literature research 

“Follow the PICO scheme.” This is the recommendation of many auditors and reviewers, as well as some regulatory documents (such as MDCG guidelines and MEDDEV 2.7/1 rev.4), regarding precise medical literature searches.  Read in this article,  1. PICO scheme: The basics  1.1 Definition  The topic is structured according to four aspects:     Aspect  Explanation  P …

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